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Cessation of Antibiotics for Complicated Appendicitis at Discharge Does Not Increase Risk of Post-operative Infection

Video Published 2024-07-10 Updated 2024-07-10

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Topic Overview

Study from Utah demonstrates that discontinuing antibiotics at discharge for complicated appendicitis patients does not increase rates of deep organ space infections or surgical site infections compared to continuing home antibiotics. Findings support antibiotic stewardship by safely eliminating post-discharge antibiotic courses in this population.

Key Takeaways

  • Discontinuing antibiotics at discharge for complicated appendicitis does not increase post-operative infection rates
  • No significant difference in deep organ space infections or SSIs between home antibiotic vs no antibiotic groups
  • Protocol change safely eliminated home antibiotics in 121 complicated appendicitis patients without adverse outcomes
  • Length of stay remained unchanged regardless of post-discharge antibiotic use
  • Evidence supports antibiotic stewardship by avoiding unnecessary post-discharge antibiotics in complicated appendicitis

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