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Postoperative Antibiotics, Outcomes, and Resource Use in Children With Gangrenous Appendicitis

Video Published 2024-04-29 Updated 2024-04-29

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Topic Overview

Multi-center retrospective study from the Eastern Pediatric Surgery Network found no significant difference in surgical site infections or readmission rates between children receiving postoperative antibiotics versus no antibiotics after non-perforated appendicitis. Results suggest postoperative antibiotics may be unnecessary in this population, supporting antibiotic stewardship efforts.

Key Takeaways

  • Multi-center study found no difference in surgical site infections between antibiotic vs no antibiotic groups after non-perforated appendicitis
  • 30-day readmission rates were similar regardless of post-operative antibiotic use in non-perforated appendicitis cases
  • Propensity-matched analysis (n=202 per group) supports omitting post-op antibiotics for non-perforated appendicitis
  • Eastern Pediatric Surgery Network data suggests post-operative antibiotics may be unnecessary resource use in this population

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