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BOB in Ped Surg - Lourenzo Sbragia, IBEROAMERICANA - Presentation

Video Published 2023-02-06 Updated 2023-02-13

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Topic Overview

Multi-center cohort study (18 years, n=53) examining outcomes in neonatal short bowel syndrome and ultra-short bowel syndrome. Mortality was 57%, with TPN duration and failure to achieve enteral adaptation identified as key predictors of death. NEC was the most common etiology (55%).

Key Takeaways

  • Short bowel syndrome mortality in neonates is 57% in this cohort; NEC accounts for 55% of cases requiring extensive resection.
  • Total parenteral nutrition duration directly impacts survival—shorter TPN exposure during adaptation improves outcomes.
  • Ultra-short bowel (<25cm) has worse prognosis than short bowel (25-60cm); achieving enteral adaptation is critical for survival.
  • Premature infants (75% of cohort) with short bowel require central venous access and prolonged nutritional support.
  • Time to definitive surgery and discharge weight are predictive factors for mortality in neonatal short bowel syndrome.

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