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Dr. Todd Ponsky

Pediatric Surgery · View profile →

Decrease Surgical Site Infections

Video Published 2019-12-17 Updated 2024-02-10

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Topic Overview

Columbus Children's Hospital reduced wound infection rates after stoma takedown from 21% to 2% through a perioperative bundle and antibiotic switch from cefoxitin to ertapenem. Published in Journal of Pediatric Surgery, October 2019, demonstrating significant improvement in surgical site infection prevention.

Key Takeaways

  • Perioperative bundle for stoma takedown reduced wound infection rate from 21% to 8% (Norton et al., 2017)
  • Switching antibiotics from cefoxitin to Unasyn further decreased infection rate to 2% (JPS, October 2019)
  • Antibiotic selection is a critical modifiable factor in preventing surgical site infections after stoma closure
  • Bundled interventions combined with optimized antimicrobial prophylaxis achieve superior infection control outcomes

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