STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial
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- Primary anastomosis reduces parenteral nutrition duration vs. stoma in NEC infants requiring bowel resection (12-center RCT, 2010-2020)
- No difference in mortality or unplanned reoperations between anastomosis and stoma groups in the STAT trial
- Primary anastomosis appears superior for enhancing recovery without increasing adverse outcomes in NEC requiring laparotomy
- STAT trial provides Level 1 evidence favoring anastomosis over stoma formation as initial surgical approach for resectable NEC
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What's the best surgical approach for infants needing laparotomy for necrotizing enterocolitis, anaesthmosis, or stoma formation? I'm Lizzie Lee from Cincinnati Children's Hospital, and this is an article you should know about. The stat trial was a randomized controlled trial in 12 centers worldwide that looked at newborns who underwent laparotomy for necrotizing enterocolitis requiring intestinal resection from 2010 to 2020. They were randomized to two surgical approaches, either anasthmosis or stoma formation. They found that the infants undergoing primary anasthmosis had a significantly less duration of requiring parental nutrition compared to those with stoma formation without a difference in mortality or unplanned surgeries. This suggests that primary anasthmosis is superior for enhancing recovery from necrotizing enterocolitis in infants and does not increase adverse outcomes. Let us know what you think in the comments below and stay tuned for more articles that you should know about.