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Clinical Characteristics and Postoperative Functional Outcomes in Children With Mowat-Wilson Syndrome and Hirschsprung's Disease: A Single-center Study

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Topic overview

This single-center study examines postoperative functional outcomes in pediatric patients with Mowat-Wilson Syndrome-associated Hirschsprung disease compared to isolated Hirschsprung cases. The research addresses a gap in prognostic data for this rare genetic condition affecting approximately half of MWS patients.

Key takeaways

  • Mowat-Wilson Syndrome is autosomal dominant; ~50% of MWS patients present with Hirschsprung's Disease
  • This single-center study compares postoperative outcomes in MWS+HSCR vs isolated HSCR patients
  • First nested case-control study examining prognosis correlation in this patient population
  • Focus on mid-to-short-term functional outcomes following surgical intervention

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How to cite: GlobalCastMD. Clinical Characteristics and Postoperative Functional Outcomes in Children With Mowat-Wilson Syndrome and Hirschsprung's Disease: A Single-center Study. GlobalCastMD Medical Library. 2025-01-29. https://dev.library.globalcastmd.com/article/9730?via_space=staycurrentmd

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