Nutritional support in children treated for advanced adrenocortical carcinoma
Topic overview
This retrospective study examines nutritional support needs in pediatric patients with advanced adrenocortical carcinoma undergoing multimodal chemotherapy. Over half of patients required enteral or parenteral nutrition due to treatment-related gastrointestinal toxicity, with younger children at higher risk. The authors recommend considering preemptive feeding tube placement to prevent treatment delays.
Key takeaways
- 54.5% of pediatric patients with advanced ACC required supplemental nutrition (enteral or parenteral) during multimodal chemotherapy treatment.
- Patients needing nutritional support experienced mean weight loss of 13.8% and required support for average 362 days during treatment course.
- Younger patients (mean age 4.45 vs 9.14 years) were more likely to require nutritional supplementation during ACC treatment.
- Preemptive feeding tube placement should be considered in advanced ACC patients to prevent treatment delays from poor oral intake.
- Cisplatin-based chemotherapy regimens for ACC cause significant GI toxicity that frequently prevents adequate oral nutrition intake.
Keywords
Hashtags
Full article text
Full article text not available for this entry
How to cite: GlobalCastMD. Nutritional support in children treated for advanced adrenocortical carcinoma. GlobalCastMD Medical Library. 2025-01-23. https://dev.library.globalcastmd.com/article/9693?via_space=staycurrentmd
Comments