Short-term postoperative complications in preterm neonates with surgical necrotizing enterocolitis: a multicenter retrospective cohort study
Topic overview
This multicenter study of 326 preterm neonates who underwent surgery for necrotizing enterocolitis found a 57% postoperative complication rate within 30 days, with sepsis, stoma-related issues, and wound dehiscence being most common. Cardiovascular support prior to surgery increased risk of major complications, while stoma creation was associated with minor complications.
Key takeaways
- 57% of preterm neonates with surgical NEC experience postoperative complications within 30 days, with 19% mortality rate.
- Most common complications are sepsis (19%), stoma-related issues (13%), and wound dehiscence (11%).
- Cardiovascular support between diagnosis and surgery doubles the risk of major postoperative complications (OR 1.92).
- Stoma creation increases risk of minor complications 6-fold compared to primary anastomosis (OR 6.73).
- These complication rates provide evidence-based data for preoperative parental counseling in surgical NEC cases.
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How to cite: GlobalCastMD. Short-term postoperative complications in preterm neonates with surgical necrotizing enterocolitis: a multicenter retrospective cohort study. GlobalCastMD Medical Library. 2024-12-20. https://dev.library.globalcastmd.com/article/9561?via_space=staycurrentmd
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