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Clinical translation of tissue-engineered oesophageal grafts: are patients ready for us?

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Topic overview

This study assessed patient and caregiver attitudes toward tissue-engineered oesophageal grafts for long-gap oesophageal atresia through an engagement event with 43 respondents. Results showed strong receptivity, with 89% comfortable with cell cultivation and perceptions significantly improving after education about the technology. The findings support establishing patient focus groups to guide clinical translation of tissue-engineered constructs for OA treatment.

Key takeaways

  • 85% of OA patients/caregivers had awareness of tissue engineering, indicating readiness for clinical translation discussions.
  • 89% reported no concerns about growing their own cells in a lab for tissue-engineered oesophageal grafts.
  • Patient perception of tissue engineering significantly improved after education (median score 4→5, p<0.0001).
  • 96% of attendees wanted involvement in focus groups for developing tissue-engineered products for oesophageal atresia.
  • Early stakeholder engagement is essential for successful clinical translation of tissue-engineered constructs.

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How to cite: GlobalCastMD. Clinical translation of tissue-engineered oesophageal grafts: are patients ready for us?. GlobalCastMD Medical Library. 2024-11-06. https://dev.library.globalcastmd.com/article/9392?via_space=staycurrentmd

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