Survival rate changes in children with congenital diaphragmatic hernia over the past three decades: a nationwide, population-based prospective nested case–control study
Topic overview
This Swedish population-based study tracked survival outcomes for 684 children with congenital diaphragmatic hernia over three decades (1982-2015), demonstrating significant improvements in 2-year survival rates for both premature and term infants. Despite progress, CDH patients still face 5.8 times higher mortality risk compared to controls.
Key takeaways
- CDH 2-year survival improved significantly over 3 decades (1982-2015), though mortality remains 5.8× higher than controls.
- 70.4% of CDH patients survived to age 2, compared to 99.6% of controls in this Swedish population-based study.
- CDH patients had 4× higher prematurity rate (23.3% vs 6.1%), but survival improved for both premature and term infants.
- Survival gains occurred across all gestational ages, suggesting advances in neonatal intensive care and surgical management.
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How to cite: GlobalCastMD. Survival rate changes in children with congenital diaphragmatic hernia over the past three decades: a nationwide, population-based prospective nested case–control study. GlobalCastMD Medical Library. 2024-11-01. https://dev.library.globalcastmd.com/article/9375?via_space=staycurrentmd
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