STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial
Topic overview
The STAT trial compared two surgical approaches for necrotizing enterocolitis requiring bowel resection in neonates across 12 centers. Primary anastomosis led to significantly faster recovery from parenteral nutrition and fewer intestinal complications compared to stoma formation, with no difference in mortality rates.
Key takeaways
- Primary anastomosis reduces parenteral nutrition duration vs stoma in NEC requiring resection (HR 2.38, p=0.004)
- No mortality difference between primary anastomosis and stoma formation in neonatal NEC surgery
- Stoma formation associated with higher rate of multiple intestinal complications compared to primary anastomosis
- When distal bowel is healthy at NEC laparotomy, primary anastomosis is preferred over stoma creation
- Primary anastomosis enhances recovery without increasing adverse outcomes in appropriately selected NEC cases
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How to cite: GlobalCastMD. STAT trial: stoma or intestinal anastomosis for necrotizing enterocolitis: a multicentre randomized controlled trial. GlobalCastMD Medical Library. 2024-10-29. https://dev.library.globalcastmd.com/article/9352?via_space=staycurrentmd
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