Role of Emerging Urinary Biomarkers in Predicting Progressive Deterioration of Kidney Function in Congenital Anomalies of Kidney and Urinary Tract: Trefoil Family Factor 3, Alpha Soluble Klotho and Urinary Microalbuminuria
Topic overview
This article examines novel urinary biomarkers—trefoil family factor 3, alpha soluble klotho, and microalbuminuria—for early detection of progressive kidney function decline in patients with congenital kidney and urinary tract anomalies. These markers may enable clinicians to identify at-risk CAKUT patients before irreversible chronic kidney disease develops.
Key takeaways
- CAKUT patients face irreversible progression to chronic kidney disease, requiring early risk stratification.
- Trefoil Family Factor 3, alpha soluble Klotho, and microalbuminuria are emerging urinary biomarkers for CAKUT progression.
- These biomarkers rise early in disease process, enabling identification of at-risk patients before significant function loss.
- Early biomarker detection allows targeted intervention to slow progressive renal decline in CAKUT populations.
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How to cite: GlobalCastMD. Role of Emerging Urinary Biomarkers in Predicting Progressive Deterioration of Kidney Function in Congenital Anomalies of Kidney and Urinary Tract: Trefoil Family Factor 3, Alpha Soluble Klotho and Urinary Microalbuminuria. GlobalCastMD Medical Library. 2024-10-19. https://dev.library.globalcastmd.com/article/9329?via_space=staycurrentmd
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