Utility of the oxygenation index in management of congenital diaphragmatic hernia: a report from a Thai University Surgical Centre
Topic overview
This retrospective study of 55 CDH newborns demonstrates that oxygenation index measured during the first 72 hours of life strongly predicts mortality and need for advanced ventilation. Higher OI values correlated with preoperative death and guided surgical timing decisions in a Thai tertiary center.
Key takeaways
- Higher oxygenation index (OI) in first 72 hours correlates with CDH mortality and need for high-frequency oscillatory ventilation
- OI on day 2 of life significantly predicts preoperative mortality risk in CDH newborns (42.1 vs 14.9 in survivors, p=0.04)
- Non-survivors had consistently elevated OI across days 1-3 compared to survivors (31.6 vs 10.5 on day 1, p<0.05)
- Serial OI monitoring can guide ventilatory management decisions and optimal timing for surgical repair in CDH patients
- Study of 55 CDH cases showed 40% mortality with OI trends strongly predictive of cardiorespiratory outcomes
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How to cite: GlobalCastMD. Utility of the oxygenation index in management of congenital diaphragmatic hernia: a report from a Thai University Surgical Centre. GlobalCastMD Medical Library. 2024-10-05. https://dev.library.globalcastmd.com/article/9253?via_space=staycurrentmd
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