Surgical treatment of invasive pulmonary fungal infections in immunocompromised pediatric patients: Aspergillus spp. and other emerging fungi
Topic overview
This retrospective study examines surgical management of invasive pulmonary fungal infections in 25 immunocompromised children, predominantly with acute leukemia. Lung resection showed zero surgery-related mortality and prevented recurrence in 84% of survivors, with Aspergillus being the most common pathogen identified.
Key takeaways
- Surgical resection of invasive pulmonary fungal infections in immunocompromised children had 0% surgery-related mortality in this series.
- Surgery should be considered for persistent/worsening IPFI or asymptomatic lesions before intensive chemotherapy or stem cell transplant.
- Non-specific CT consolidations suggest non-Aspergillus fungi; Aspergillus typically presents with more characteristic imaging findings.
- Atypical lung resections were sufficient in 96% of cases, preserving lung parenchyma while achieving source control.
- Early surgical intervention may prevent disseminated fungal infection in high-risk immunocompromised pediatric patients.
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How to cite: GlobalCastMD. Surgical treatment of invasive pulmonary fungal infections in immunocompromised pediatric patients: Aspergillus spp. and other emerging fungi. GlobalCastMD Medical Library. 2024-10-05. https://dev.library.globalcastmd.com/article/9250?via_space=staycurrentmd
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