Factors predicting the need for liver transplantation in biliary atresia patients after 18 years of age

Topic overview

Key takeaways

• APRI score at age 18 is the most useful predictor of future liver transplant need in biliary atresia patients (AUC 0.91).
• MELD scores at 18 years did not significantly differ between native liver survivors and those requiring later transplantation.
• APRI, ALBI, and BALF scores at age 18 were significantly elevated in patients who subsequently required liver transplantation.
• Adult BA patients face limited transplant options due to donor scarcity, making prognostic markers for transplant need critical.
• Age at Kasai procedure and BA type did not predict need for transplantation after 18 years in native liver survivors.

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