Liver Mitochondrial Morphology and Gene Expression as Markers of Liver Reserve: Prognostic Implications for Native Liver Survival in Biliary Atresia

This study examines hepatocyte mitochondrial structure and gene expression patterns in biliary atresia patients compared to other cholestatic conditions and normal liver tissue to identify prognostic markers for native liver survival. The research aims to determine whether mitochondrial characteristics can predict clinical outcomes and inform transplantation timing decisions in pediatric patients with biliary atresia.