Clinical characteristics and outcome of omphalocele and gastroschisis: a 20-year multicenter regional experience
Topic overview
This 20-year Hong Kong multicenter study reviews 85 cases of omphalocele and gastroschisis, reporting surgical management approaches, associated anomalies, and long-term outcomes. Most patients achieved normal development with overall survival rates of 85.9% for omphalocele and 92.9% for gastroschisis, providing valuable prognostic data for antenatal counseling.
Key takeaways
- Omphalocele has higher mortality (14.1%) than gastroschisis (7.1%) and is frequently associated with cardiac (39.4%) and chromosomal defects (15.5%).
- Primary repair was achieved in 53.5% of omphalocele and 64.3% of gastroschisis cases; staged closure averaged 8-9 days of silo reduction.
- Long-term outcomes are favorable: 92.5% had normal intellectual development and 79.2% normal growth at mean 77-month follow-up.
- Gastroschisis has lower complication rate (21.4%) compared to omphalocele (36.6%), with intestinal atresia occurring in 7.1% of gastroschisis cases.
- Overall survival rate is good for both conditions when managed surgically, providing reassuring data for antenatal and postnatal parental counseling.
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How to cite: GlobalCastMD. Clinical characteristics and outcome of omphalocele and gastroschisis: a 20-year multicenter regional experience. GlobalCastMD Medical Library. 2024-07-25. https://dev.library.globalcastmd.com/article/8923?via_space=staycurrentmd
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