Analysis of wound infections among pediatric patients following the 2023 Türkiye–Syria earthquakes
Topic overview
Retrospective analysis of 180 pediatric earthquake victims identifies blood transfusion requirement as strongest predictor of wound infection (OR=9.9), with 81% gram-negative pathogens showing multidrug resistance. Laboratory thresholds for CK, liver enzymes, and inflammatory markers demonstrate high negative predictive value for infection risk stratification in mass-casualty scenarios.
Key takeaways
- 12.2% of pediatric earthquake injury patients developed wound infections, with blood transfusion need being the strongest predictor (OR=9.9).
- Gram-negative pathogens caused 81% of wound infections, with 75% showing multidrug or extensive drug resistance patterns.
- Normal lab values (CK<810, CRP<45.8, AST<32) had high negative predictive value (93-100%) for ruling out wound infection development.
- Crush syndrome, fasciotomy, amputation, and invasive devices significantly increased wound infection risk in trapped pediatric patients.
- Broad-spectrum empiric antibiotics should target resistant gram-negatives in high-risk pediatric disaster victims with collapse exposure.
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How to cite: GlobalCastMD. Analysis of wound infections among pediatric patients following the 2023 Türkiye–Syria earthquakes. GlobalCastMD Medical Library. 2024-07-17. https://dev.library.globalcastmd.com/article/8875?via_space=staycurrentmd
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