Urological outcomes in adult females born with anorectal malformation or Hirschsprung disease

Topic overview

Key takeaways

• Adult females with cloaca have significantly higher rates of urinary incontinence, UTIs, and social impairment versus reference population.
• 26.6% of ARM/HD patients required bladder reconstruction; 18.8% perform catheterization through channel or native urethra.
• Chronic kidney disease or ESRD affects a subset of patients, with three requiring kidney transplantation in this cohort.
• Cloaca subgroup requires lifelong multidisciplinary follow-up including urology and nephrology for urologic sequelae management.
• Self-reported urinary outcomes demonstrate persistent morbidity into adulthood, emphasizing need for transition care protocols.

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