The postoperative renal function of persistent cloaca patients treated by posterior sagittal anorecto-urethro-vaginopalsty: results of a nationwide survey in Japan
Topic overview
Nationwide Japanese study of 103 persistent cloaca patients post-PSARUVP found 45.6% developed reduced renal function (CKD Stage ≥2), with vesicoureteral reflux identified as the primary modifiable risk factor. Early VUR detection and aggressive bladder management may preserve long-term kidney function in this complex patient population.
Key takeaways
- 45.6% of persistent cloaca patients post-PSARUVP develop chronic kidney disease (Stage ≥2), indicating significant long-term renal risk.
- Vesicoureteral reflux is a key modifiable risk factor—significantly associated with renal function decline, UTIs, and bladder dysfunction.
- Early VUR assessment and aggressive bladder management are critical to preserving renal function in persistent cloaca patients.
- Hydrocolpos and renal anomalies show trends toward renal decline, warranting close prenatal and postnatal monitoring.
- Vesicostomy use correlates with worse renal outcomes, possibly reflecting disease severity rather than causation.
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How to cite: GlobalCastMD. The postoperative renal function of persistent cloaca patients treated by posterior sagittal anorecto-urethro-vaginopalsty: results of a nationwide survey in Japan. GlobalCastMD Medical Library. 2024-07-06. https://dev.library.globalcastmd.com/article/8813?via_space=staycurrentmd
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