Duodenal Atresia in Finland from 2004 to 2017: Prevalence, Mortality, and Associated Anomalies—A Population-Based Study
Topic overview
This Finnish population-based study (2004-2017) reports a duodenal atresia prevalence of 3.08/10,000 births with 95% one-year survival. One-third of cases were syndromic, with trisomy 21 present in 25.3% and cardiac anomalies in 36.1%, the latter associated with increased mortality.
Key takeaways
- DA prevalence in Finland: 2.75/10,000 live births, stable 2004-2017; 40% isolated cases, 33% syndromic, 27% multiple anomalies.
- Trisomy 21 present in 25% of DA cases; cardiac anomalies most common (36%), followed by GI tract anomalies (24%) and limb defects (7%).
- Excellent survival: 96.4% neonatal survival, 95% alive at 1 year; mortality strongly associated with cardiac anomalies.
- No terminations occurred in isolated DA cases; all 11 terminations involved syndromic or multiple anomaly presentations.
- 89% resulted in live births despite prenatal diagnosis capability; cardiac workup essential given 36% cardiac anomaly rate.
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How to cite: GlobalCastMD. Duodenal Atresia in Finland from 2004 to 2017: Prevalence, Mortality, and Associated Anomalies—A Population-Based Study. GlobalCastMD Medical Library. 2024-06-21. https://dev.library.globalcastmd.com/article/8763?via_space=staycurrentmd
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