Management and Outcomes of Hepatoblastoma in Patients With Trisomy 18: A Systematic Review and Pooled Analysis of 70 Patients
Topic overview
This systematic review analyzes 70 cases of hepatoblastoma in children with trisomy 18, examining treatment approaches and survival outcomes. The study addresses the clinical management of this rare combination, providing evidence to guide oncologic decision-making in this chromosomally complex patient population.
Key takeaways
- 1-year survival in trisomy 18 has improved to 59.3%, changing the landscape for oncologic management decisions.
- Hepatoblastoma occurs in children with trisomy 18, requiring tailored treatment approaches given underlying syndrome.
- Systematic review of 70 patients provides evidence base for managing this rare dual-diagnosis population.
- Outcomes data can guide multidisciplinary discussions about treatment intensity in T18 patients with hepatoblastoma.
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How to cite: GlobalCastMD. Management and Outcomes of Hepatoblastoma in Patients With Trisomy 18: A Systematic Review and Pooled Analysis of 70 Patients. GlobalCastMD Medical Library. 2024-06-10. https://dev.library.globalcastmd.com/article/8723?via_space=staycurrentmd
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