Risk factors for post-operative portal vein stenosis in pediatric liver transplantation: a single center case-control study
Topic overview
This case-control study identifies cryopreserved vein grafts and young donor age as independent risk factors for portal vein stenosis following pediatric liver transplantation. Among 332 patients, cryopreserved grafts showed 55% stenosis rates versus 0% with fresh grafts, highlighting critical technical considerations in pediatric vascular reconstruction.
Key takeaways
- Portal vein stenosis occurs in 10.5% of pediatric liver transplant recipients, with incidence varying by reconstruction technique.
- Cryopreserved vein grafts have 55% PVS rate versus 0% with fresh iliac vein grafts—avoid cryopreserved grafts when possible.
- Liver donors under 12 years old carry 18.8% PVS risk, nearly double the overall rate—an independent risk factor.
- Fresh vein graft interposition is superior to cryopreserved grafts for portal vein reconstruction in pediatric transplantation.
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How to cite: GlobalCastMD. Risk factors for post-operative portal vein stenosis in pediatric liver transplantation: a single center case-control study. GlobalCastMD Medical Library. 2024-04-26. https://dev.library.globalcastmd.com/article/8552?via_space=staycurrentmd
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