How effective is nephrectomy in curing hypertension in children with unilateral poorly functioning kidney? A systematic review
Topic overview
This systematic review examines whether removing a poorly functioning kidney can cure hypertension in children, analyzing 88 pediatric cases. Nephrectomy successfully resolved hypertension in approximately two-thirds of children, with vesicoureteral reflux being the most common underlying cause.
Key takeaways
- Nephrectomy cures hypertension in 65.9% of children with unilateral poorly functioning kidney, avoiding long-term antihypertensive medication.
- Unilateral atrophic kidney with/without VUR accounts for 43% of PFK cases causing pediatric hypertension.
- Laparoscopic nephrectomy is increasingly utilized and may be first-line surgical approach for PFK-related hypertension in children.
- Follow-up of 1.5-3.3 years demonstrates sustained blood pressure control in two-thirds of children post-nephrectomy.
- Renovascular pathology accounts for 22% of PFK cases; UPJ obstruction and MCDK together represent 35% of etiologies.
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How to cite: GlobalCastMD. How effective is nephrectomy in curing hypertension in children with unilateral poorly functioning kidney? A systematic review. GlobalCastMD Medical Library. 2024-04-03. https://dev.library.globalcastmd.com/article/8473?via_space=staycurrentmd
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