Antegrade Continence Enema Alone for the Management of Functional Constipation and Segmental Colonic Dysmotility (ACE-FC): A Pediatric Colorectal and Pelvic Learning Consortium Study

Topic overview

Key takeaways

• ACE alone successfully managed 92% of pediatric patients with severe functional constipation and segmental colonic dysmotility at 1-year follow-up.
• Only 8% of patients required subsequent colonic resection after ACE, demonstrating its effectiveness as initial surgical management.
• Absence of pelvic floor dyssynergia on anorectal manometry was significantly associated with higher likelihood of needing colonic resection.
• ACE can help the majority of patients with documented segmental colonic dysmotility avoid more extensive colonic resection procedures.
• Multi-institutional data supports ACE as first-line surgical intervention before considering segmental colectomy in this patient population.

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