Reply to Letter to the Editor by Kaya C, et al.
Topic overview
The authors respond to methodological concerns about their necrotizing enterocolitis study, acknowledging limitations of the retrospective design and surgeon variability in bowel resection decisions. They note attempts to control for confounders using demographic data and nSOFA scores, while recognizing unmeasured factors may influence outcomes.
Key takeaways
- Study limitations include retrospective design and lack of randomization, allowing for multiple confounding factors.
- Surgical decision-making (extent of necrotic bowel resection) was at individual surgeon's discretion, introducing variability.
- Authors attempted to control confounders using demographic data and nSOFA score but acknowledge incomplete adjustment.
- Unmeasured factors may still influence study findings despite statistical controls applied.
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How to cite: GlobalCastMD. Reply to Letter to the Editor by Kaya C, et al.. GlobalCastMD Medical Library. 2024-03-28. https://dev.library.globalcastmd.com/article/8387?via_space=staycurrentmd
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