The Extent of the Transition Zone in Hirschsprung's Disease

This study quantifies the histological transition zone in Hirschsprung's disease, finding it extends a median of 8 cm in all patients and up to 13 cm in rectosigmoid cases. The findings suggest surgeons should resect at least 5 cm beyond the most distal ganglionic biopsy to avoid retained transition zone and postoperative obstructive symptoms.