Fulminant Necrosis of the Colon Associated With Antegrade Continence Enemas

Topic overview

Key takeaways

• Fulminant colonic necrosis is a rare but severe complication of antegrade continence enema (ACE) therapy in pediatric patients.
• Two adolescent males with repaired anorectal malformations developed this life-threatening complication years after appendicostomy.
• Clinicians using ACE for fecal incontinence management must maintain high vigilance for acute abdominal symptoms suggesting bowel ischemia.
• Early recognition and surgical intervention are critical when colonic necrosis occurs in ACE patients to prevent mortality.

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